CARDARINE (GW501516)

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What is Cardarine?

Cardarine, also known as GW501516, is a revolutionary compound found in the family of Selective Androgen Receptor Modulators (SARMs). It was originally developed to treat numerous metabolic diseases but has since become one of the most popular SARMs on the market. Its unique and powerful effects stem from its ability to activate AMP-activated protein kinase (AMPK) which activates fatty acid oxidation in the mitochondria. This allows for increased endurance, improved aerobic performance and reduced body fat. Additionally, Cardarine has been shown to lower cholesterol levels significantly, reduce inflammation throughout the body and protect against age-related diseases like Alzheimer’s disease and diabetes.

Benefits & Results

Cardarine, or GW501516, is a powerful Selective Androgen Receptor Modulator (SARM) that can provide multiple health and performance benefits to those who take it. In particular, the following five benefits have been observed in clinical studies and trials:

• Increased Endurance and Improved Athletic Performance

Cardarine has been shown to enhance athletic performance by increasing endurance levels and improving aerobic power. This benefit was first discovered during a study on lab animals where it was found that animals taking cardarine had an improved ability to run longer distances as compared to those not taking it. The effects of cardarine in terms of increased exercise endurance were also observed in human studies, with participants taking the compound being able to run up to 20 percent farther than they had previously been able to.

• Reduced Body Fat and Increased Baseline Metabolism

Cardarine has also been demonstrated to reduce body fat levels while increasing the body’s basal metabolic rate (BMR). Through its activation of pathways such as AMPK which control fat burning in the body, cardarine can reduce adipose tissue and increase metabolism. In animal studies, this resulted in less stored fat overall as well as an increased resting metabolic rate even after the compound was discontinued. Thus, cardarine can be seen as a viable aid for those looking to reduce their body fat levels naturally while boosting their metabolic rate.

• Reduction in Cholesterol Levels

One of the key benefits associated with using cardarine is its ability to lower cholesterol levels in the body. This is due to its influence on certain enzymes such as Lipoprotein Lipase (LPL) which are involved in lipid metabolism within cells. Studies have shown that when subjects took cardarine for thirty days straight, their total cholesterol levels decreased significantly compared with placebo results. This could result in long-term improvements for the cardiovascular system overall if continued use of cardarine is present over a longer period of time.

• Reduced Inflammation throughout the body

In addition to its influence on cholesterol levels, cardarine has also been observed to reduce inflammation throughout the entire body. Animal studies have revealed that when treated with GW501516, macrophages produced fewer pro-inflammatory cytokines which are associated with inflammation processes such as allergies or arthritis pain relief. Thus, through regular use of cardarine, users may expect a decrease in their overall inflammation markers providing relief from chronic pains caused by inflammatory conditions such as osteoarthritis or rheumatoid arthritis.

Cardarine Dosage

It is recommended to take 10-20mg of GW501516 per day. It should be ideally taken in the morning as it can increase energy and might affect sleeping pattern if taken late at night. Cardarine should be taken for a period of 12-16 weeks for optimal results.

References

1. Exercise in a Pill: The Latest on Exercise-Mimetics
2. A metabolomic study of the PPARδ agonist  for enhancing running endurance
3. Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist